Synthetic Cannabanoids: Found in K2, Spice, Spike99, EZIncense
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Synthetic Cannabanoids: Found in K2, Spice, Spike99, EZIncense

Synthetic Cannabanoids: K2, Spice, EZIncense.com Herbal Incense

There has been a lot of "buzz" about this stuff out there lately. K2, Spice Diamond, Spike99, EzIncense, are to name a few that are out there. I wanted to post a few things for people to know about this stuff.

Recreational use of these substances has been growing in popularity. The chemicals are spread on random plant material and packaged sometimes as fragrant, mood affecting incense. Compared to the natural marijuana market though, these synthetics are fairly uncommon.

The human body produces endogenous cannabinoids and the cannabis plant produces exogenous cannabinoids. We have a complex cannabinoid receptor system throughout our bodies. Marijuana contains a variety of unique cannabinoids that bind with these receptors. Synthetic cannabinoids have been created to study the receptor system in animals and humans.

Some of these compounds have been sold to the public and federal authorities seem to be cracking down on the newfound legal high. The Food and Drug Administration or FDA insists that sale for human consumption is not approved.

Jahan Marcu is currently conducting research at Temple University and is one of the few cannabinoid scientists in America. He was familiar with Spice.

“There are a variety of cannabinoids… there are the classical plant cannabinoids that most of us are familiar with; they’re known as tri-cyclic cannabinoids like THC or Marinol. The JWH-018 is a very new compound, it was synthesized in 1998 and it belongs to an ‘indol’ family of cannabinoids. And these indol derivatives have been very powerful research tools in the last decade and have really advanced cannabinoid science. There are hundreds if not thousands of these synthesized cannabinoids.”

Somehow a few of those compounds made it from the labs onto the streets and not just in the US, but also around the world.

“When we see these things starting to appear in designer drugs or herbal (products) it is a concern because not much is known about these compounds. They are very new and are used to test receptor function.”

Marcu explained that JWH-018 is a standard ingredient, but not the only thing in Spice.

Paul Armentano is the Deputy Director of national NORML and a respected author on the topic of cannabinoids. We spoke with him yesterday. Paul explained that the frontal lobe of the brain has a dense concentration of CB1 cannabinoid receptors. The JWH-018 and other synthetic cannabinoids are likely activating those receptors.

But if you smoked these synthetics would you pass a workplace or other current, standard drug screen?

“Yes.”

This fact may be the real reason behind the drug’s growing appeal. Users are beating the system at it’s own game. Unlike the tens of millions of regular marijuana consumers in the country, the synthetic users are legally and in full privacy, activating their cannabinoid receptors at will. The cost of introducing a new set of screening to the drug tests administered nationwide would be hefty.

Though it may seem like a clean getaway for the Spicers there are some serious unknowns. The most pressing questions regard the untested impact long-term ingestion of these synthetic cannabinoids can have on individuals.

We have 6,000 years of humans ingesting natural marijuana. We know that natural cannabis is non-toxic and can call it ‘safe’ for most individuals using it for medication or recreation. But humans have been using these new chemicals for less than 15 years.

Cannabinoid researcher Marcu points out that Spice and K2 are not a consistent product by any means, even with their main ingredient.

“In Japan they surveyed over 40 herbal preparations on the market and JWH-018 ranged from 2.0 to over 35 milligrams in a gram of this ‘spice’ substance. So it varies widely.”

But for community leaders and potential users of this new drug the question is of safety.

“We don’t know,” Marcu said. “There is just so little known about these compounds. The actual compound could be safe but the metabolites could somehow be pharmacologically active.”

Both Amrentano and Marcu pointed out several different scientifically generated synthetic cannabinoids, hundreds in fact. Marcu said even with current crackdown on JWH-018, law enforcement would have a difficult time keeping all of these synthetic cannabinoid derivatives off of the street.

Marijuana reform advocates point to the rise in popularity of Spice as another unfortunate by-product of natural cannabis prohibition.

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Comments (4)
Poke Smot

We offer better infused incense at even a better price than K2, Spice, Spike99, Serenity, etc. Check out our website!

ezincense.com

k2 incense

It's important to buy it from somewhere that is verified because just like with anything else, there is already a lot of counterfeit k2 floating around.

Robert

I would just like to put my experiences with this product out there. I have been using Marijuana for many many years now although this product Is similar to the effects of weed it is not the same. People need to understand that like any substance (caffeine, food, alcohol,.....) If abused or mis understood/misused can have adverse potentially life threatening side effects. Always know what you are doing and use in moderation or it can be harmful

in some way..Duh! rather than try to make every substance on the planet Illegal and put Innocent Americans in jail because the government cant respect peoples privacy (that is supposed to be protected by our Constitution)that is wrong. Some day if we continue this way we could be put in jail for coffee or a hamburger, why not they can kill you. Basically what I'm saying is if you don't know what you are doing dont use this product and if you do the research use caution. The truth is that this substance if properly used can have the same Positive medicinal benefits of Medical Marijuana. I personally think that this has the potential of being a better option than Marijuana for many reasons. One, it is cheaper(compared to the balloned value of Marijuana). second, there are different types of this substance that effect the body/mind in different ways due to the selective affinity to the cannabinoid receptors depending on the chemical. which means it could have many medicinal values. Third, to get the desired effect you dont have to smoke it. It can be effectivly and safely broken down into liquid form using grain alcohol (95%/v edible corn alcohol), and applied to food or your favorite drink. You just need to calculate the mixture to be able to understand the dosage. IE: 1g added to 100ml or 3.39 ounces of grain alcohol = 10mg/ml. Smoking this substance is effective but not recomended, due to the fact that you are changing the chemical composition and possibly introducing unwanted chemicals and carcinogens. not to mention is much harder to get an accurate dose due to the fact that it is active smoked at only .5mg and to accurately measure that size of dose you need a super expensive scale. cheap scales are not the way to go due to accuracy in small doses. When taking orally an effective dose of 018 is around 10mg but is imperative to dilute in grain alcohol (using other solvent can pose a danger including rubbing alcohol DANGEROUS!)Grain alcohol is the same as potent vodka, edible but use responsibly. And just add to a drink or food like you would hash or Marijuana extracts, It takes more than smoking but has less side effects. Smoked dose equals 1-4mg "good luck measuring that" or Orally dose equals 10-20mg diluted in alcohol 1g+100ml=10mg/ml so the dose should be measured at 1-2ml. You can get a ml measuring dropper usually from any pharmacy for free or very cheap just ask the pharmacist. That is the safest way to effectively use and measure this substance safely with no known side effects different than Marijuana IE: red eyes, munchies, short term memory, and possible anxiety. Everyone needs to understand that its not the substance that is harmful, Its the person using it. just like a gun. not everyone should have one due to mental problems, stupidity, or lack of knowledge. becaus you may harm yourself or others. But educated sane people should be allowed if they know what they are doing. I agree that like Marijuana, alcohol, cigg's...... should be regulated in some sense to keep out of reach of children and young adults who are immature and don't know what they are doing. but to others should be a right. how is this substance or Marijuana different or more harmful than Alcohol? other than the fact that more than likely you wont loose control and beat up your wife or children like you may on alcohol. To me its a little bit of an oxymoron to say that alcohol is safe but this or marijuana isn't and people should go to jail for having it. That is just stupid propaganda made by stupid people, and supported by stupid people. Basically, this is a human rights problem no different than slavery or segregation. IE: you can become a prisoner for possession and forced to be locked up against your will. you must pass a drug test to be able to get most jobs, yet anyone who abuses alcohol is fine and those who take prescription drugs (even if that drug is similar in effects or worse physically addictive) those are ok, no matter the side effects(some deadly). Yet these are highly discriminated against. It makes sense to me "NOT". But i guess we as a society will never be perfect. Anyone who believes that is not only stupid but a hypocrite. Lets free America again. Back to our original values. Stop turning innocent Americans into criminals. Stop privatizing prisons/jails, definitely don't let judges benefit financially from convictions or owning a stake in a private jail. Free all Americans who are jailed for cannabinoid substances (jwh,Marijuana)."FREE AMERICA!"

Robert

I would just like to put my experiences with this product out there. I have been using Marijuana for many many years now although this product Is similar to the effects of weed it is not the same. People need to understand that like any substance (caffeine, food, alcohol,.....) If abused or mis understood/misused can have adverse potentially life threatening side effects. Always know what you are doing and use in moderation or it can be harmful

in some way..Duh! rather than try to make every substance on the planet Illegal and put Innocent Americans in jail because the government cant respect peoples privacy (that is supposed to be protected by our Constitution)that is wrong. Some day if we continue this way we could be put in jail for coffee or a hamburger, why not they can kill you. Basically what I'm saying is if you don't know what you are doing dont use this product and if you do the research use caution. The truth is that this substance if properly used can have the same Positive medicinal benefits of Medical Marijuana. I personally think that this has the potential of being a better option than Marijuana for many reasons. One, it is cheaper(compared to the balloned value of Marijuana). second, there are different types of this substance that effect the body/mind in different ways due to the selective affinity to the cannabinoid receptors depending on the chemical. which means it could have many medicinal values. Third, to get the desired effect you dont have to smoke it. It can be effectivly and safely broken down into liquid form using grain alcohol (95%/v edible corn alcohol), and applied to food or your favorite drink. You just need to calculate the mixture to be able to understand the dosage. IE: 1g added to 100ml or 3.39 ounces of grain alcohol = 10mg/ml. Smoking this substance is effective but not recomended, due to the fact that you are changing the chemical composition and possibly introducing unwanted chemicals and carcinogens. not to mention is much harder to get an accurate dose due to the fact that it is active smoked at only .5mg and to accurately measure that size of dose you need a super expensive scale. cheap scales are not the way to go due to accuracy in small doses. When taking orally an effective dose of 018 is around 10mg but is imperative to dilute in grain alcohol (using other solvent can pose a danger including rubbing alcohol DANGEROUS!)Grain alcohol is the same as potent vodka, edible but use responsibly. And just add to a drink or food like you would hash or Marijuana extracts, It takes more than smoking but has less side effects. Smoked dose equals 1-4mg "good luck measuring that" or Orally dose equals 10-20mg diluted in alcohol 1g+100ml=10mg/ml so the dose should be measured at 1-2ml. You can get a ml measuring dropper usually from any pharmacy for free or very cheap just ask the pharmacist. That is the safest way to effectively use and measure this substance safely with no known side effects different than Marijuana IE: red eyes, munchies, short term memory, and possible anxiety. Everyone needs to understand that its not the substance that is harmful, Its the person using it. just like a gun. not everyone should have one due to mental problems, stupidity, or lack of knowledge. becaus you may harm yourself or others. But educated sane people should be allowed if they know what they are doing. I agree that like Marijuana, alcohol, cigg's...... should be regulated in some sense to keep out of reach of children and young adults who are immature and don't know what they are doing. but to others should be a right. how is this substance or Marijuana different or more harmful than Alcohol? other than the fact that more than likely you wont loose control and beat up your wife or children like you may on alcohol. To me its a little bit of an oxymoron to say that alcohol is safe but this or marijuana isn't and people should go to jail for having it. That is just stupid propaganda made by stupid people, and supported by stupid people. Basically, this is a human rights problem no different than slavery or segregation. IE: you can become a prisoner for possession and forced to be locked up against your will. you must pass a drug test to be able to get most jobs, yet anyone who abuses alcohol is fine and those who take prescription drugs (even if that drug is similar in effects or worse physically addictive) those are ok, no matter the side effects(some deadly). Yet these are highly discriminated against. It makes sense to me "NOT". But i guess we as a society will never be perfect. Anyone who believes that is not only stupid but a hypocrite. Lets free America again. Back to our original values. Stop turning innocent Americans into criminals. Stop privatizing prisons/jails, definitely don't let judges benefit financially from convictions or owning a stake in a private jail. Free all Americans who are jailed for cannabinoid substances (jwh,Marijuana)."FREE AMERICA!"

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